The Pattern of Cortical Dysfunction in a Mouse Model of a Schizophrenia-Related Microdeletion

We used a mouse model of the schizophrenia-predisposing 22q11.2 microdeletion to evaluate how this genetic lesion affects cortical neural circuits at the synaptic, cellular, and molecular levels. Guided by cognitive deficits, we demonstrated that mutant mice display robust deficits in high-frequency...

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Detalhes bibliográficos
Main Authors: Fénelon, Karine, Xu, Bin, Lai, Cora S., Mukai, Jun, Markx, Sander, Stark, Kimberly L., Hsu, Pei-Ken, Gan, Wen-Biao, Fischbach, Gerald D., MacDermott, Amy B., Karayiorgou, Maria, Gogos, Joseph A.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2013
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3771024/
https://ncbi.nlm.nih.gov/pubmed/24027283
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1611-13.2013
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