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Derepression of a novel neuronal inhibitor is a major outcome of miRNA dysregulation due to 22q11.2 microdeletion
22q11.2 microdeletions result in specific cognitive deficits and schizophrenia. Analysis of Df(16)A(+/−) mice, which model this microdeletion, revealed abnormalities in the formation of neuronal dendrites and spines, as well as altered brain microRNAs. Here we show a drastic reduction of miR-185, wh...
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| Autores principales: | , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2013
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3556818/ https://ncbi.nlm.nih.gov/pubmed/23332760 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2012.11.052 |
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