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Deficiency of Dgcr8, a gene disrupted by the 22q11.2 microdeletion, results in altered short-term plasticity in the prefrontal cortex

Individuals with 22q11.2 microdeletions have cognitive and behavioral impairments and the highest known genetic risk for developing schizophrenia. One gene disrupted by the 22q11.2 microdeletion is DGCR8, a component of the “microprocessor” complex that is essential for microRNA production, resultin...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Fénelon, Karine, Mukai, Jun, Xu, Bin, Hsu, Pei-Ken, Drew, Liam J., Karayiorgou, Maria, Fischbach, Gerald D., MacDermott, Amy B., Gogos, Joseph A.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: National Academy of Sciences 2011
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC3060227/
https://ncbi.nlm.nih.gov/pubmed/21368174
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1101219108
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