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Role of kappa-opioid receptors in stress and anxiety-related behavior

RATIONALE: Accumulating evidence indicates that brain kappa-opioid receptors (KORs) and dynorphin, the endogenous ligand that binds at these receptors, are involved in regulating states of motivation and emotion. These findings have stimulated interest in the development of KOR-targeted ligands as t...

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Bibliographic Details
Main Authors: Van't Veer, Ashlee, Carlezon, William A.
Format: Artigo
Language:Inglês
Published: 2013
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3770816/
https://ncbi.nlm.nih.gov/pubmed/23836029
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00213-013-3195-5
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