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Development of Kappa Opioid Receptor Antagonists
Kappa opioid receptors (KORs) belong to the G-protein coupled class of receptors (GPCRs). They are activated by the endogenous opioid peptide dynorphin (DYN) and expressed at particularly high levels within brain areas implicated in modulation of motivation, emotion, and cognitive function. Chronic...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3612131/ https://ncbi.nlm.nih.gov/pubmed/23360448 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm301783x |
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