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Development of Kappa Opioid Receptor Antagonists

Kappa opioid receptors (KORs) belong to the G-protein coupled class of receptors (GPCRs). They are activated by the endogenous opioid peptide dynorphin (DYN) and expressed at particularly high levels within brain areas implicated in modulation of motivation, emotion, and cognitive function. Chronic...

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Bibliografiska uppgifter
Huvudupphovsmän: Carroll, F. Ivy, Carlezon, William A.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2013
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3612131/
https://ncbi.nlm.nih.gov/pubmed/23360448
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm301783x
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