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Development of Kappa Opioid Receptor Antagonists

Kappa opioid receptors (KORs) belong to the G-protein coupled class of receptors (GPCRs). They are activated by the endogenous opioid peptide dynorphin (DYN) and expressed at particularly high levels within brain areas implicated in modulation of motivation, emotion, and cognitive function. Chronic...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Carroll, F. Ivy, Carlezon, William A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3612131/
https://ncbi.nlm.nih.gov/pubmed/23360448
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm301783x
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