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Role of kappa-opioid receptors in stress and anxiety-related behavior

RATIONALE: Accumulating evidence indicates that brain kappa-opioid receptors (KORs) and dynorphin, the endogenous ligand that binds at these receptors, are involved in regulating states of motivation and emotion. These findings have stimulated interest in the development of KOR-targeted ligands as t...

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Detalhes bibliográficos
Main Authors: Van't Veer, Ashlee, Carlezon, William A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3770816/
https://ncbi.nlm.nih.gov/pubmed/23836029
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00213-013-3195-5
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