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Development, clinical utility, and place of ivacaftor in the treatment of cystic fibrosis

Cystic fibrosis (CF) is a life-limiting, multisystem disease characterized by thick viscous secretions leading to recurrent lung infections, bronchiectasis, and progressive deterioration in lung function. CF is caused by loss or dysfunction of the CF transmembrane conductance regulator (CFTR) protei...

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Detaylı Bibliyografya
Asıl Yazarlar: O’Reilly, Ruth, Elphick, Heather E
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Dove Medical Press 2013
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3770629/
https://ncbi.nlm.nih.gov/pubmed/24039402
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S30345
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