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The safety of lumacaftor and ivacaftor for the treatment of cystic fibrosis

INTRODUCTION: Lumacaftor-ivacaftor is indicated for treatment of cystic fibrosis (CF) in patients homozygous for the Phe-508del cystic fibrosis transmembrane conductance regulator (CFTR) gene mutations. In clinical trials, treated patients showed improved pulmonary function, reduced pulmonary exacer...

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Detalhes bibliográficos
Publicado no:Expert Opin Drug Saf
Main Authors: Guevera, Maria Talamo, McColley, Susanna A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6209511/
https://ncbi.nlm.nih.gov/pubmed/28846049
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/14740338.2017.1372419
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