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The safety of lumacaftor and ivacaftor for the treatment of cystic fibrosis
INTRODUCTION: Lumacaftor-ivacaftor is indicated for treatment of cystic fibrosis (CF) in patients homozygous for the Phe-508del cystic fibrosis transmembrane conductance regulator (CFTR) gene mutations. In clinical trials, treated patients showed improved pulmonary function, reduced pulmonary exacer...
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| Published in: | Expert Opin Drug Saf |
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| Main Authors: | , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
2017
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6209511/ https://ncbi.nlm.nih.gov/pubmed/28846049 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/14740338.2017.1372419 |
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