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Safety and efficacy of treatment with lumacaftor in combination with ivacaftor in younger patients with cystic fibrosis
INTRODUCTION: Cystic fibrosis (CF) is the most common autosomal recessive disorder affecting approximately 70,000 people worldwide. The lack of functional cystic fibrosis transmembrane conductance regulator (CFTR) causes dysregulation of epithelial fluid transport in the lungs, gastrointestinal trac...
Gardado en:
| Publicado en: | Expert Rev Respir Med |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2019
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6482058/ https://ncbi.nlm.nih.gov/pubmed/30929526 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/17476348.2019.1602040 |
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