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Development, clinical utility, and place of ivacaftor in the treatment of cystic fibrosis
Cystic fibrosis (CF) is a life-limiting, multisystem disease characterized by thick viscous secretions leading to recurrent lung infections, bronchiectasis, and progressive deterioration in lung function. CF is caused by loss or dysfunction of the CF transmembrane conductance regulator (CFTR) protei...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Dove Medical Press
2013
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3770629/ https://ncbi.nlm.nih.gov/pubmed/24039402 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S30345 |
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