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The emerging family of CULLIN3-RING ubiquitin ligases (CRL3s): cellular functions and disease implications

Protein ubiquitylation is a post-translational modification that controls all aspects of eukaryotic cell functionality, and its defective regulation is manifested in various human diseases. The ubiquitylation process requires a set of enzymes, of which the ubiquitin ligases (E3s) are the substrate r...

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Detalhes bibliográficos
Principais autores: Genschik, Pascal, Sumara, Izabela, Lechner, Esther
Formato: Artigo
Idioma:Inglês
Publicado em: European Molecular Biology Organization 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3770339/
https://ncbi.nlm.nih.gov/pubmed/23912815
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2013.173
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