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The emerging family of CULLIN3-RING ubiquitin ligases (CRL3s): cellular functions and disease implications
Protein ubiquitylation is a post-translational modification that controls all aspects of eukaryotic cell functionality, and its defective regulation is manifested in various human diseases. The ubiquitylation process requires a set of enzymes, of which the ubiquitin ligases (E3s) are the substrate r...
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| Auteurs principaux: | , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
European Molecular Biology Organization
2013
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3770339/ https://ncbi.nlm.nih.gov/pubmed/23912815 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2013.173 |
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