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Autophagy sequesters damaged lysosomes to control lysosomal biogenesis and kidney injury
Diverse causes, including pathogenic invasion or the uptake of mineral crystals such as silica and monosodium urate (MSU), threaten cells with lysosomal rupture, which can lead to oxidative stress, inflammation, and apoptosis or necrosis. Here, we demonstrate that lysosomes are selectively sequester...
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| 主要な著者: | , , , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
European Molecular Biology Organization
2013
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3770333/ https://ncbi.nlm.nih.gov/pubmed/23921551 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2013.171 |
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