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Pharmacological Activity of Retinoic Acid Receptor Alpha-Selective Antagonists in Vitro and in Vivo
[Image: see text] Oral administration of a retinoic acid receptor (RAR) pan-antagonist reversibly inhibits spermatogenesis. Given the importance of RARα in regulating spermatogenesis, we identified two RARα-selective antagonists by transactivation and transactivation competition assays and asked whe...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Chemical Society
2013
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| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3770188/ https://ncbi.nlm.nih.gov/pubmed/24040487 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ml300365k |
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