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Prolonged Oral Administration of a Pan-Retinoic Acid Receptor Antagonist Inhibits Spermatogenesis in Mice With a Rapid Recovery and Changes in the Expression of Influx and Efflux Transporters

We have previously shown that oral administration of a pan-retinoic acid receptor antagonist in mice daily at 2.5 mg/kg for 4 weeks reversibly inhibited spermatogenesis, with no detectable side effects. To elucidate the lowest dose and the longest dosing regimen that inhibits spermatogenesis but res...

詳細記述

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書誌詳細
出版年:Endocrinology
主要な著者: Chung, Sanny S. W., Wang, Xiangyuan, Wolgemuth, Debra J.
フォーマット: Artigo
言語:Inglês
出版事項: Endocrine Society 2016
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4816726/
https://ncbi.nlm.nih.gov/pubmed/26812157
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2015-1675
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