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Suppression of Survival Signalling Pathways by the Phosphatase PHLPP

The recently discovered PH (pleckstrin homology) domain Leucine rich repeat Protein Phosphatase (PHLPP) family is emerging as a central component in suppressing cell survival pathways. Originally discovered in a rational search for a phosphatase that directly dephosphorylates and inactivates Akt, PH...

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Autori principali: O'Neill, Audrey K., Niederst, Matthew J., Newton, Alexandra C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3770140/
https://ncbi.nlm.nih.gov/pubmed/22340730
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1742-4658.2012.08537.x
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