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Protein phosphatase PHLPP1 controls the light-induced resetting of the circadian clock
The pleckstrin homology domain leucine-rich repeat protein phosphatase 1 (PHLPP1) differentially attenuates Akt, PKC, and ERK1/2 signaling, thereby controlling the duration and amplitude of responses evoked by these kinases. PHLPP1 is expressed in the mammalian central clock, the suprachiasmatic nuc...
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| 主要な著者: | , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
National Academy of Sciences
2010
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2824391/ https://ncbi.nlm.nih.gov/pubmed/20080691 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0910292107 |
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