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R-Loop Formation In Trans at an AGGAG Repeat

Formation of RNA-DNA hybrid, or R-loop, was studied in vitro by transcribing an AGGAG repeat with T7 RNA polymerase. When ribonuclease T1 was present, R-loop formation in cis was diminished, indicating that the transcript was separated from the template and reassociated with it. The transcript was f...

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Detalhes bibliográficos
Main Authors: Toriumi, Kazuya, Tsukahara, Takuma, Hanai, Ryo
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3770058/
https://ncbi.nlm.nih.gov/pubmed/24066229
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2013/629218
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