Determinants of R-loop formation at convergent bidirectionally transcribed trinucleotide repeats

R-loops have been described at immunoglobulin class switch sequences, prokaryotic and mitochondrial replication origins, and disease-associated (CAG)n and (GAA)n trinucleotide repeats. The determinants of trinucleotide R-loop formation are unclear. Trinucleotide repeat expansions cause diseases incl...

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Bibliographic Details
Main Authors: Reddy, Kaalak, Tam, Mandy, Bowater, Richard P., Barber, Miriam, Tomlinson, Matthew, Nichol Edamura, Kerrie, Wang, Yuh-Hwa, Pearson, Christopher E.
Format: Artigo
Language:Inglês
Published: Oxford University Press 2011
Subjects:
Molecular Biology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3061079/
https://ncbi.nlm.nih.gov/pubmed/21051337
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkq935
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