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Hybridization of RNA to double-stranded DNA: formation of R-loops.

RNA can hybridize to double-stranded DNA in the presence of 70% formamide by displacing the identical DNA strand. The resulting structure, called an R-loop, is formed in formamide probably because of the greater thermodynamic stability of the RNA-DNA hybrid when it is near the denaturation temperatu...

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Bibliografske podrobnosti
Main Authors: Thomas, M, White, R L, Davis, R W
Format: Artigo
Jezik:Inglês
Izdano: 1976
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC430535/
https://ncbi.nlm.nih.gov/pubmed/781674
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