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The Angiopoietin-like Proteins ANGPTL3 and ANGPTL4 Inhibit Lipoprotein Lipase Activity through Distinct Mechanisms

Two members of the angiopoietin-like family of proteins, ANGPTL3 and ANGPTL4, have been shown to play important roles in modulating lipoprotein metabolism in the body. Both proteins were found to suppress lipoprotein lipase (LPL) activity in vitro as well as in vivo. However, their mechanisms of inh...

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Autori principali: Shan, Lu, Yu, Xuan-Chuan, Liu, Ziye, Hu, Yi, Sturgis, Lydia T., Miranda, Maricar L., Liu, Qingyun
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2009
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3769808/
https://ncbi.nlm.nih.gov/pubmed/19028676
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M808477200
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