ANGPTL8 promotes the ability of ANGPTL3 to bind and inhibit lipoprotein lipase

OBJECTIVE: Several members of the angiopoietin-like (ANGPTL) family of proteins, including ANGPTL3 and ANGPTL8, regulate lipoprotein lipase (LPL) activity. Deficiency in either ANGPTL3 or ANGPTL8 reduces plasma triglyceride levels and increases LPL activity, whereas overexpression of either protein...

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Detalhes bibliográficos
Publicado no:Mol Metab
Main Authors: Chi, Xun, Britt, Emily C., Shows, Hannah W., Hjelmaas, Alexander J., Shetty, Shwetha K., Cushing, Emily M., Li, Wendy, Dou, Alex, Zhang, Ren, Davies, Brandon S.J.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2017
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5641604/
https://ncbi.nlm.nih.gov/pubmed/29031715
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmet.2017.06.014
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