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Novel GPIHBP1-independent pathway for clearance of plasma TGs in Angptl4(−/−)Gpihbp1(−/−) mice
Mice lacking glycosylphosphatidylinositol-anchored HDL-binding protein 1 (GPIHBP1) are unable to traffic LPL to the vascular lumen. Thus, triglyceride (TG) clearance is severely blunted, and mice are extremely hypertriglyceridemic. Paradoxically, mice lacking both GPIHBP1 and the LPL regulator, angi...
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| Veröffentlicht in: | J Lipid Res |
|---|---|
| Hauptverfasser: | , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
The American Society for Biochemistry and Molecular Biology
2018
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6027919/ https://ncbi.nlm.nih.gov/pubmed/29739862 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M084749 |
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