GPIHBP1 stabilizes lipoprotein lipase and prevents its inhibition by angiopoietin-like 3 and angiopoietin-like 4

Glycosylphosphatidylinositol-anchored HDL-binding protein (GPIHBP1) binds both LPL and chylomicrons, suggesting that GPIHBP1 is a platform for LPL-dependent processing of triglyceride (TG)-rich lipoproteins. Here, we investigated whether GPIHBP1 affects LPL activity in the absence and presence of LP...

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Detalhes bibliográficos
Main Authors: Sonnenburg, William K., Yu, Daiguan, Lee, E-Chiang, Xiong, Wei, Gololobov, Gennady, Key, Billie, Gay, Jason, Wilganowski, Nat, Hu, Yi, Zhao, Sharon, Schneider, Matthias, Ding, Zhi-Ming, Zambrowicz, Brian P., Landes, Greg, Powell, David R., Desai, Urvi
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Biochemistry and Molecular Biology 2009
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2781314/
https://ncbi.nlm.nih.gov/pubmed/19542565
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M900145-JLR200
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