Temporal Dynamics of Clonal Evolution in Chronic Lymphocytic Leukemia with Stereotyped IGHV4-34/IGKV2-30 Antigen Receptors: Longitudinal Immunogenetic Evidence

Chronic lymphocytic leukemia (CLL) patients assigned to stereotyped subset 4 possess distinctive patterns of intraclonal diversification (ID) within their immunoglobulin (IG) genes. Although highly indicative of an ongoing response to antigen(s), the critical question concerning the precise timing o...

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Main Authors: Sutton, Lesley-Ann, Kostareli, Efterpi, Stalika, Evangelia, Tsaftaris, Athanasios, Anagnostopoulos, Achilles, Darzentas, Nikos, Rosenquist, Richard, Stamatopoulos, Kostas
Formato: Artigo
Idioma:Inglês
Publicado em: ScholarOne 2013
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3769528/
https://ncbi.nlm.nih.gov/pubmed/23922244
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2119/molmed.2013.00042
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