An Entity Evolving into a Community: Defining the Common Ancestor and Evolutionary Trajectory of Chronic Lymphocytic Leukemia Stereotyped Subset #4

Patients with chronic lymphocytic leukemia (CLL) assigned to stereotyped subset #4 express highly homologous B-cell receptor immunoglobulin (BcR IG) sequences with intense intraclonal diversification (ID) in the context of ongoing somatic hypermutation (SHM). Their remarkable biological and clinical...

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Publicat a:Mol Med
Autors principals: Sutton, Lesley-Ann, Papadopoulos, Giorgos, Hadzidimitriou, Anastasia, Papadopoulos, Stavros, Kostareli, Efterpi, Rosenquist, Richard, Tzovaras, Dimitrios, Stamatopoulos, Kostas
Format: Artigo
Idioma:Inglês
Publicat: ScholarOne 2015
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Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4398667/
https://ncbi.nlm.nih.gov/pubmed/25486132
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2119/molmed.2014.00140
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