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Immunoglobulin Gene Repertoire in Chronic Lymphocytic Leukemia: Insight into Antigen Selection and Microenvironmental Interactions

Immunogenetic analysis of the B cell receptors (BCRs) has been a richly rewarding field for unraveling the pathogenesis of human lymphomas, including CLL. A biased immunoglobulin gene repertoire is seen as evidence for selection of CLL progenitor cells by antigen. Additional corroborative evidence i...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Kostareli, Efterpi, Gounari, Maria, Agathangelidis, Andreas, Stamatopoulos, Kostas
Format: Artigo
Sprache:Inglês
Veröffentlicht: Università Cattolica del Sacro Cuore 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3435129/
https://ncbi.nlm.nih.gov/pubmed/22973496
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4084/MJHID.2012.052
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