High-density screening reveals a different spectrum of genomic aberrations in chronic lymphocytic leukemia patients with ‘stereotyped’ IGHV3-21 and IGHV4-34 B-cell receptors

BACKGROUND: The existence of multiple subsets of chronic lymphocytic leukemia expressing ‘stereotyped’ B-cell receptors implies the involvement of antigen(s) in leukemogenesis. Studies also indicate that ‘stereotypy’ may influence the clinical course of patients with chronic lymphocytic leukemia, fo...

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Detalhes bibliográficos
Main Authors: Marincevic, Millaray, Cahill, Nicola, Gunnarsson, Rebeqa, Isaksson, Anders, Mansouri, Mahmoud, Göransson, Hanna, Rasmussen, Markus, Jansson, Mattias, Ryan, Fergus, Karlsson, Karin, Adami, Hans-Olov, Davi, Fred, Jurlander, Jesper, Juliusson, Gunnar, Stamatopoulos, Kostas, Rosenquist, Richard
Formato: Artigo
Idioma:Inglês
Publicado em: Ferrata Storti Foundation 2010
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2930953/
https://ncbi.nlm.nih.gov/pubmed/20421269
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2009.021014
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