Colonic 15-PGDH levels are stable across distance and time, and are not perturbed by aspirin intervention

BACKGROUND & AIMS: 15-hydroxprostaglandin dehydrogenase (15-PGDH) mediates a colon neoplasia suppressor pathway, acting through metabolic antagonism of cyclooxygenase (COX)-mediated colon carcinogenesis. To determine whether the colon tumor prevention activity of 15-PGDH acts as a constant or va...

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Autori principali: Fink, Stephen P., Yang, Dong-Hoon, Barnholtz-Sloan, Jill S., Ryu, Yeon-Mi, Mikkola, Debra, Potter, John D., Lampe, Johanna W., Markowitz, Sanford D., Myung, Seung-Jae
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2013
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3769508/
https://ncbi.nlm.nih.gov/pubmed/23625286
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10620-013-2670-5
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