Tissue-specific patterns of gene expression in the epithelium and stroma of normal colon in healthy individuals in an aspirin intervention trial

BACKGROUND: Regular aspirin use reduces colon adenoma and carcinoma incidence. UDP-glucuronosyltransferases (UGT) are involved in aspirin metabolism and clearance, and variant alleles in UGT1A6 have been shown to alter salicylic acid metabolism and risk of colon neoplasia. METHODS: In a randomized,...

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Bibliografski detalji
Izdano u:BMC Med Genet
Glavni autori: Thomas, Sushma S, Makar, Karen W, Li, Lin, Zheng, Yingye, Yang, Peiying, Levy, Lisa, Rudolph, Rebecca Yvonne, Lampe, Paul D, Yan, Min, Markowitz, Sanford D, Bigler, Jeannette, Lampe, Johanna W, Potter, John D
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2015
Teme:
Research Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4422425/
https://ncbi.nlm.nih.gov/pubmed/25927723
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12881-015-0161-6
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