Tissue-specific patterns of gene expression in the epithelium and stroma of normal colon in healthy individuals in an aspirin intervention trial

BACKGROUND: Regular aspirin use reduces colon adenoma and carcinoma incidence. UDP-glucuronosyltransferases (UGT) are involved in aspirin metabolism and clearance, and variant alleles in UGT1A6 have been shown to alter salicylic acid metabolism and risk of colon neoplasia. METHODS: In a randomized,...

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Udgivet i:BMC Med Genet
Main Authors: Thomas, Sushma S, Makar, Karen W, Li, Lin, Zheng, Yingye, Yang, Peiying, Levy, Lisa, Rudolph, Rebecca Yvonne, Lampe, Paul D, Yan, Min, Markowitz, Sanford D, Bigler, Jeannette, Lampe, Johanna W, Potter, John D
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2015
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4422425/
https://ncbi.nlm.nih.gov/pubmed/25927723
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12881-015-0161-6
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