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Tissue-specific patterns of gene expression in the epithelium and stroma of normal colon in healthy individuals in an aspirin intervention trial

BACKGROUND: Regular aspirin use reduces colon adenoma and carcinoma incidence. UDP-glucuronosyltransferases (UGT) are involved in aspirin metabolism and clearance, and variant alleles in UGT1A6 have been shown to alter salicylic acid metabolism and risk of colon neoplasia. METHODS: In a randomized,...

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Detalhes bibliográficos
Publicado no:BMC Med Genet
Main Authors: Thomas, Sushma S, Makar, Karen W, Li, Lin, Zheng, Yingye, Yang, Peiying, Levy, Lisa, Rudolph, Rebecca Yvonne, Lampe, Paul D, Yan, Min, Markowitz, Sanford D, Bigler, Jeannette, Lampe, Johanna W, Potter, John D
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4422425/
https://ncbi.nlm.nih.gov/pubmed/25927723
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12881-015-0161-6
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