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MEK inhibition affects STAT3 signaling and invasion in human melanoma cell lines
Elevated activity of the MAPK signaling cascade is found in the majority of human melanomas and is known to regulate proliferation, survival, and invasion. Current targeted therapies focus on decreasing the activity of this pathway; however, we do not fully understand how these therapies impact tumo...
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| 主要な著者: | , , , , , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2013
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3769503/ https://ncbi.nlm.nih.gov/pubmed/23624919 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2013.131 |
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