MEK inhibition affects STAT3 signaling and invasion in human melanoma cell lines

Elevated activity of the MAPK signaling cascade is found in the majority of human melanomas and is known to regulate proliferation, survival, and invasion. Current targeted therapies focus on decreasing the activity of this pathway; however, we do not fully understand how these therapies impact tumo...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Autori principali: Vultur, Adina, Villanueva, Jessie, Krepler, Clemens, Rajan, Geena, Chen, Quan, Xiao, Min, Li, Ling, Gimotty, Phyllis A., Wilson, Melissa, Hayden, James, Keeney, Frederick, Nathanson, Katherine L., Herlyn, Meenhard
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2013
Soggetti:
Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3769503/
https://ncbi.nlm.nih.gov/pubmed/23624919
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2013.131
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi