FGF21 regulates circadian behavior and metabolism by acting on the nervous system

Fibroblast growth factor 21 (FGF21) is a hepatokine that acts as a global starvation signal to modulate fuel partitioning and metabolism, and repress growth(1); however the site of action of these diverse effects remains unclear. FGF21 signals through a heteromeric cell surface receptor composed of...

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Hlavní autoři: Bookout, Angie L., de Groot, Marleen H. M., Owen, Bryn M., Lee, Syann, Gautron, Laurent, Lawrence, Heather L., Ding, Xunshan, Elmquist, Joel K., Takahashi, Joseph S., Mangelsdorf, David J., Kliewer, Steven A.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2013
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3769420/
https://ncbi.nlm.nih.gov/pubmed/23933984
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm.3249
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