FGF21 regulates circadian behavior and metabolism by acting on the nervous system

Fibroblast growth factor 21 (FGF21) is a hepatokine that acts as a global starvation signal to modulate fuel partitioning and metabolism, and repress growth(1); however the site of action of these diverse effects remains unclear. FGF21 signals through a heteromeric cell surface receptor composed of...

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Autores principales: Bookout, Angie L., de Groot, Marleen H. M., Owen, Bryn M., Lee, Syann, Gautron, Laurent, Lawrence, Heather L., Ding, Xunshan, Elmquist, Joel K., Takahashi, Joseph S., Mangelsdorf, David J., Kliewer, Steven A.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2013
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3769420/
https://ncbi.nlm.nih.gov/pubmed/23933984
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm.3249
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