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Consequences of domain insertion on sequence-structure divergence in a superfold

Although the universe of protein structures is vast, these innumerable structures can be categorized into a finite number of folds. New functions commonly evolve by elaboration of existing scaffolds, for example, via domain insertions. Thus, understanding structural diversity of a protein fold evolv...

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Detalhes bibliográficos
Main Authors: Pandya, Chetanya, Brown, Shoshana, Pieper, Ursula, Sali, Andrej, Dunaway-Mariano, Debra, Babbitt, Patricia C., Xia, Yu, Allen, Karen N.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3767544/
https://ncbi.nlm.nih.gov/pubmed/23959887
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1305519110
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