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Quantifying hub-like behavior in protein folding networks

The free energy landscape of a protein is a function of many interdependent degrees of freedom. For this reason, conceptual constructs (e.g., funnels) have been useful to visualize these landscapes. One relatively new construct is the idea of a hub-like native state that is the final destination of...

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Autors principals: Dickson, Alex, Brooks, Charles L.
Format: Artigo
Idioma:Inglês
Publicat: 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3767461/
https://ncbi.nlm.nih.gov/pubmed/24027492
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ct300537s
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