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Coupled folding and binding with 2D Window-Exchange Umbrella Sampling

Intrinsically disordered regions of proteins can gain structure by binding to a partner. This process, of coupled folding and binding, is a fundamental part of many important biological processes. Structure-based models have proven themselves capable of revealing fundamental aspects of how coupled f...

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Detalles Bibliográficos
Publicado en:J Comput Chem
Autores principales: Dickson, Alex, Ahlstrom, Logan S., Brooks, Charles L.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2015
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4744578/
https://ncbi.nlm.nih.gov/pubmed/26250657
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcc.24004
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