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Native states of fast-folding proteins are kinetic traps
It has been suggested that the native state of a protein acts as a kinetic hub that can facilitate transitions between nonnative states. Using recently developed tools to quantify mediation probabilities (“hub scores”), we quantify hub-like behavior in atomic resolution trajectories for the first ti...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3619186/ https://ncbi.nlm.nih.gov/pubmed/23458553 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja311077u |
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