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Native states of fast-folding proteins are kinetic traps

It has been suggested that the native state of a protein acts as a kinetic hub that can facilitate transitions between nonnative states. Using recently developed tools to quantify mediation probabilities (“hub scores”), we quantify hub-like behavior in atomic resolution trajectories for the first ti...

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Bibliografische gegevens
Hoofdauteurs: Dickson, Alex, Brooks, Charles L.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2013
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3619186/
https://ncbi.nlm.nih.gov/pubmed/23458553
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja311077u
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