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Protein folded states are kinetic hubs

Understanding molecular kinetics, and particularly protein folding, is a classic grand challenge in molecular biophysics. Network models, such as Markov state models (MSMs), are one potential solution to this problem. MSMs have recently yielded quantitative agreement with experimentally derived stru...

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Bibliographic Details
Main Authors: Bowman, Gregory R., Pande, Vijay S.
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2010
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2890711/
https://ncbi.nlm.nih.gov/pubmed/20534497
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1003962107
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