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Protein folded states are kinetic hubs

Understanding molecular kinetics, and particularly protein folding, is a classic grand challenge in molecular biophysics. Network models, such as Markov state models (MSMs), are one potential solution to this problem. MSMs have recently yielded quantitative agreement with experimentally derived stru...

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Autori principali: Bowman, Gregory R., Pande, Vijay S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2890711/
https://ncbi.nlm.nih.gov/pubmed/20534497
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1003962107
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