Inhibition of Transplantation Tolerance by Immune Senescence Is Reversed by Endocrine Modulation

The senescent immune system responds poorly to new stimuli; thymic involution, accumulation of memory cells against other specificities, and general refractoriness to antigen signaling all may contribute to poor resistance to infection. These same changes may pose a significant clinical barrier to o...

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Hlavní autoři: Zhao, Gaoping, Moore, Daniel J., Kim, James I., Lee, Kang Mi, O’Connor, Matthew R., Duff, Patrick E., Yang, Maozhu, Lei, Ji, Markmann, James F., Deng, Shaoping
Médium: Artigo
Jazyk:Inglês
Vydáno: 2011
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3767303/
https://ncbi.nlm.nih.gov/pubmed/21677198
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.3002270
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