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Inhibition of Transplantation Tolerance by Immune Senescence Is Reversed by Endocrine Modulation
The senescent immune system responds poorly to new stimuli; thymic involution, accumulation of memory cells against other specificities, and general refractoriness to antigen signaling all may contribute to poor resistance to infection. These same changes may pose a significant clinical barrier to o...
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| 主要な著者: | , , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2011
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3767303/ https://ncbi.nlm.nih.gov/pubmed/21677198 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.3002270 |
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