Role of the eNOS-NO System in Regulating the Antiproteinuric Effects of VEGF Receptor 2 Inhibition in Diabetes

Subtle perturbations in intraglomerular VEGF/VEGFR-2 signaling or in the influencing microenvironment can profoundly affect renal function, resulting in the apparently paradoxical observation that VEGF blockade attenuates proteinuria development in experimental diabetes despite exerting the opposite...

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Detalles Bibliográficos
Main Authors: Advani, Andrew, Connelly, Kim A., Advani, Suzanne L., Thai, Kerri, Zhang, Yuan, Kelly, Darren J., Gilbert, Richard E.
Formato: Artigo
Idioma:Inglês
Publicado: Hindawi Publishing Corporation 2013
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3766587/
https://ncbi.nlm.nih.gov/pubmed/24063000
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2013/201475
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