FMNL2 Drives Actin-Based Protrusion and Migration Downstream of Cdc42

Cell migration entails protrusion of lamellipodia, densely packed networks of actin filaments at the cell front. Filaments are generated by nucleation, likely mediated by Arp2/3 complex and its activator Scar/WAVE [1]. It is unclear whether formins contribute to lamellipodial actin filament nucleati...

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Hoofdauteurs: Block, Jennifer, Breitsprecher, Dennis, Kühn, Sonja, Winterhoff, Moritz, Kage, Frieda, Geffers, Robert, Duwe, Patrick, Rohn, Jennifer L., Baum, Buzz, Brakebusch, Cord, Geyer, Matthias, Stradal, Theresia E.B., Faix, Jan, Rottner, Klemens
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Cell Press 2012
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3765947/
https://ncbi.nlm.nih.gov/pubmed/22608513
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2012.03.064
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