FMNL formins boost lamellipodial force generation

Migration frequently involves Rac-mediated protrusion of lamellipodia, formed by Arp2/3 complex-dependent branching thought to be crucial for force generation and stability of these networks. The formins FMNL2 and FMNL3 are Cdc42 effectors targeting to the lamellipodium tip and shown here to nucleat...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Nat Commun
Hlavní autoři: Kage, Frieda, Winterhoff, Moritz, Dimchev, Vanessa, Mueller, Jan, Thalheim, Tobias, Freise, Anika, Brühmann, Stefan, Kollasser, Jana, Block, Jennifer, Dimchev, Georgi, Geyer, Matthias, Schnittler, Hans-Joachim, Brakebusch, Cord, Stradal, Theresia E. B., Carlier, Marie-France, Sixt, Michael, Käs, Josef, Faix, Jan, Rottner, Klemens
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2017
Témata:
Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5364437/
https://ncbi.nlm.nih.gov/pubmed/28327544
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms14832
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky