Induced Arp2/3 Complex Depletion Increases FMNL2/3 Formin Expression and Filopodia Formation

The Arp2/3 complex generates branched actin filament networks operating in cell edge protrusion and vesicle trafficking. Here we employ a conditional knockout mouse model permitting tissue- or cell-type specific deletion of the murine Actr3 gene (encoding Arp3). A functional Actr3 gene appeared esse...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Front Cell Dev Biol
Egile Nagusiak: Dimchev, Vanessa, Lahmann, Ines, Koestler, Stefan A., Kage, Frieda, Dimchev, Georgi, Steffen, Anika, Stradal, Theresia E. B., Vauti, Franz, Arnold, Hans-Henning, Rottner, Klemens
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Frontiers Media S.A. 2021
Gaiak:
Cell and Developmental Biology
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7882613/
https://ncbi.nlm.nih.gov/pubmed/33598464
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2021.634708
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