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The structure of FMNL2–Cdc42 yields insights into the mechanism of lamellipodia and filopodia formation
Formins are actin polymerization factors that elongate unbranched actin filaments at the barbed end. Rho family GTPases activate Diaphanous-related formins through the relief of an autoregulatory interaction. The crystal structures of the N-terminal domains of human FMNL1 and FMNL2 in complex with a...
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| Publicado no: | Nat Commun |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Pub. Group
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4432619/ https://ncbi.nlm.nih.gov/pubmed/25963737 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms8088 |
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