RhoG and Cdc42 can contribute to Rac-dependent lamellipodia formation through WAVE regulatory complex-binding

Cell migration frequently involves the formation of lamellipodial protrusions, the initiation of which requires Rac GTPases signalling to heteropentameric WAVE regulatory complex (WRC). While Rac-related RhoG and Cdc42 can potently stimulate lamellipodium formation, so far presumed to occur by upstr...

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Bibliografiske detaljer
Udgivet i:Small GTPases
Main Authors: Schaks, Matthias, Döring, Hermann, Kage, Frieda, Steffen, Anika, Klünemann, Thomas, Blankenfeldt, Wulf, Stradal, Theresia, Rottner, Klemens
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 2019
Fag:
Brief Report
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7849749/
https://ncbi.nlm.nih.gov/pubmed/31451035
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/21541248.2019.1657755
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