ITGB5 and AGFG1 variants are associated with severity of airway responsiveness

BACKGROUND: Airway hyperresponsiveness (AHR), a primary characteristic of asthma, involves increased airway smooth muscle contractility in response to certain exposures. We sought to determine whether common genetic variants were associated with AHR severity. METHODS: A genome-wide association study...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Himes, Blanca E, Qiu, Weiliang, Klanderman, Barbara, Ziniti, John, Senter-Sylvia, Jody, Szefler, Stanley J, Lemanske, Jr, Robert F, Zeiger, Robert S, Strunk, Robert C, Martinez, Fernando D, Boushey, Homer, Chinchilli, Vernon M, Israel, Elliot, Mauger, David, Koppelman, Gerard H, Nieuwenhuis, Maartje AE, Postma, Dirkje S, Vonk, Judith M, Rafaels, Nicholas, Hansel, Nadia N, Barnes, Kathleen, Raby, Benjamin, Tantisira, Kelan G, Weiss, Scott T
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: BioMed Central 2013
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3765944/
https://ncbi.nlm.nih.gov/pubmed/23984888
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2350-14-86
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