ITGB5 and AGFG1 variants are associated with severity of airway responsiveness

BACKGROUND: Airway hyperresponsiveness (AHR), a primary characteristic of asthma, involves increased airway smooth muscle contractility in response to certain exposures. We sought to determine whether common genetic variants were associated with AHR severity. METHODS: A genome-wide association study...

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Hauptverfasser: Himes, Blanca E, Qiu, Weiliang, Klanderman, Barbara, Ziniti, John, Senter-Sylvia, Jody, Szefler, Stanley J, Lemanske, Jr, Robert F, Zeiger, Robert S, Strunk, Robert C, Martinez, Fernando D, Boushey, Homer, Chinchilli, Vernon M, Israel, Elliot, Mauger, David, Koppelman, Gerard H, Nieuwenhuis, Maartje AE, Postma, Dirkje S, Vonk, Judith M, Rafaels, Nicholas, Hansel, Nadia N, Barnes, Kathleen, Raby, Benjamin, Tantisira, Kelan G, Weiss, Scott T
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2013
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3765944/
https://ncbi.nlm.nih.gov/pubmed/23984888
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2350-14-86
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