ITGB5 and AGFG1 variants are associated with severity of airway responsiveness

BACKGROUND: Airway hyperresponsiveness (AHR), a primary characteristic of asthma, involves increased airway smooth muscle contractility in response to certain exposures. We sought to determine whether common genetic variants were associated with AHR severity. METHODS: A genome-wide association study...

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Detalhes bibliográficos
Main Authors: Himes, Blanca E, Qiu, Weiliang, Klanderman, Barbara, Ziniti, John, Senter-Sylvia, Jody, Szefler, Stanley J, Lemanske, Jr, Robert F, Zeiger, Robert S, Strunk, Robert C, Martinez, Fernando D, Boushey, Homer, Chinchilli, Vernon M, Israel, Elliot, Mauger, David, Koppelman, Gerard H, Nieuwenhuis, Maartje AE, Postma, Dirkje S, Vonk, Judith M, Rafaels, Nicholas, Hansel, Nadia N, Barnes, Kathleen, Raby, Benjamin, Tantisira, Kelan G, Weiss, Scott T
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3765944/
https://ncbi.nlm.nih.gov/pubmed/23984888
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2350-14-86
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