ITGB5 and AGFG1 variants are associated with severity of airway responsiveness

BACKGROUND: Airway hyperresponsiveness (AHR), a primary characteristic of asthma, involves increased airway smooth muscle contractility in response to certain exposures. We sought to determine whether common genetic variants were associated with AHR severity. METHODS: A genome-wide association study...

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מידע ביבליוגרפי
Main Authors: Himes, Blanca E, Qiu, Weiliang, Klanderman, Barbara, Ziniti, John, Senter-Sylvia, Jody, Szefler, Stanley J, Lemanske, Jr, Robert F, Zeiger, Robert S, Strunk, Robert C, Martinez, Fernando D, Boushey, Homer, Chinchilli, Vernon M, Israel, Elliot, Mauger, David, Koppelman, Gerard H, Nieuwenhuis, Maartje AE, Postma, Dirkje S, Vonk, Judith M, Rafaels, Nicholas, Hansel, Nadia N, Barnes, Kathleen, Raby, Benjamin, Tantisira, Kelan G, Weiss, Scott T
פורמט: Artigo
שפה:Inglês
יצא לאור: BioMed Central 2013
נושאים:
Research Article
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3765944/
https://ncbi.nlm.nih.gov/pubmed/23984888
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2350-14-86
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